Whenever male infertility is resistant to therapy, artificial donor insemination (AID) may be employed as a very efficient tool to provide the infertile couple with the desired child. Two hundred and seventy cases of AID were reviewed for the following information: indication for AID, age of the female partner, length and type of infertility, socioeconomic state, ovulatory pattern prior to and following initiation of the AID program, acceptance of the procedure by the male partner, and outcome of pregnancies. The over-all pregnancy rate was 85.2%. There were 159 live births, 2 perinatal deaths, 38 spontaneous abortions, 1 ectopic pregnancy, and 1 therapeutic abortion due to rubella infection. Forty patients discontinued treatment with or without notification. Treatment success was significantly affected by age of the woman, duration of infertility, socioeconomic state of the couple, and the husband's acceptance of the AID procedure. Of all pregnancies, 86.5% occurred within six treatment cycles. Repeated pregnancies required similar numbers of treatment courses per pregnancy.