TY - JOUR
T1 - Turning ON the switch - RhoGEFs in plants
AU - Shichrur, Keren
AU - Yalovsky, Shaul
N1 - Funding Information:
Research in S.Y.'s laboratory is supported by grants from The Israel Science Foundation (ISF-399/03 and ISF-Bikura-4032/02) and the Teva® prize for advancement of research.
PY - 2006/2
Y1 - 2006/2
N2 - Plant ROPs (or RACs) are Ras-related, small GTP-binding proteins that function as molecular switches in numerous signaling cascades. ROPs (RACs) cycle between a GDP-bound, inactive state and a GTP-bound, active state. Activation requires guanine-nucleotide exchange factors (GEFs), which were not identified in plants until recently. Alfred Wittinghofer and co-workers' description of a group of plant-specific RhoGEFs opens the way for the elucidation of ROP signaling cascades from membrane receptors to responses.
AB - Plant ROPs (or RACs) are Ras-related, small GTP-binding proteins that function as molecular switches in numerous signaling cascades. ROPs (RACs) cycle between a GDP-bound, inactive state and a GTP-bound, active state. Activation requires guanine-nucleotide exchange factors (GEFs), which were not identified in plants until recently. Alfred Wittinghofer and co-workers' description of a group of plant-specific RhoGEFs opens the way for the elucidation of ROP signaling cascades from membrane receptors to responses.
UR - http://www.scopus.com/inward/record.url?scp=32544447023&partnerID=8YFLogxK
U2 - 10.1016/j.tplants.2005.12.001
DO - 10.1016/j.tplants.2005.12.001
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.shortsurvey???
AN - SCOPUS:32544447023
SN - 1360-1385
VL - 11
SP - 57
EP - 59
JO - Trends in Plant Science
JF - Trends in Plant Science
IS - 2
ER -