Tumor Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Human Breast Cancer Are Mediated by PD-L1-S283 and Chemokine Axes

Keyphrases

• Chemokines 100%
• Tumor Cells 100%
• Programmed Death-ligand 1 (PD-L1) 100%
• Pro-metastatic 100%
• Human Breast Cancer 100%
• Non-cell Autonomous 100%
• Immune Suppression 11%
• Tumor 11%
• CXCL8 11%
• Triple-negative Breast Cancer 11%
• Triple-negative Breast Cancer Cells 11%
• Breast Cancer Cells 5%
• Knock 5%
• Breast Cancer Patients 5%
• Cancer Cells 5%
• T Cells 5%
• Tumor Progression 5%
• Tumor Growth 5%
• Gene-deficient Mice 5%
• Tumor Metastasis 5%
• Metastasizing 5%
• Granulocyte Colony-stimulating Factor (G-CSF) 5%
• Tumor-promoting 5%
• Tumor Cell Proliferation 5%
• Cytotoxic T-lymphocyte antigen-4 (CTLA-4) 5%
• C-C Chemokine Receptor Type 5 (CCR5) 5%
• CCL5 5%
• Tumor Cell Invasion 5%
• Chemokine Receptor 5%
• Chemokine (C-C motif) Ligand 2 (CCL2) 5%
• CCR2 5%
• Cell Release 5%
• Luminal Breast Cancer 5%
• CXCR1 5%
• Soluble Intercellular Adhesion molecule-1 (sICAM-1) 5%
• PD-L1 Expression 5%
• Human Triple Negative Breast Cancer 5%

Medicine and Dentistry

• Chemokine 100%
• Tumor Cell 100%
• Breast Cancer 100%
• Programmed Death-Ligand 1 100%
• Cancer Cell 26%
• Triple Negative Breast Cancer 26%
• Tumor Progression 20%
• Neoplasm 13%
• Immunosuppressive Treatment 13%
• Metastatic Carcinoma 6%
• T Cell 6%
• Granulocyte Macrophage Colony Stimulating Factor 6%
• CTLA-4 6%
• Knock Out 6%
• Luminal A Breast Cancer 6%
• Tumor Promotion 6%
• Chemokine Receptor CXCR1 6%