Trophoblastic tissue spread to the sigmoid colon after uterine perforation

Ishai Levin*, Dan Grisaru, David Pauzner, Benny Almog

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


BACKGROUND:: Trophoblastic tissue spread following uterine perforation during dilation and curettage is rare. We present a case of trophoblastic spread to the sigmoid colon following uterine perforation, which was treated by surgical removal of the implants and intramuscular administration of methotrexate. CASE:: A woman presented 3 weeks after curettage for a blighted ovum. Laparotomy performed for suspected intra-abdominal bleeding revealed bleeding trophoblastic implants in a perforation tract and the anterior uterine wall and on the appendix epiploica of the sigmoid colon. The implants were surgically removed and methotrexate was administered for persistently high β-hCG levels. The patient fully recovered. CONCLUSION:: Extrauterine trophoblastic implants should be considered in women evaluated for abdominal pain whose pregnancy test is positive after uterine perforation. Conservative treatment with methotrexate in nonacute patients may be considered.

Original languageEnglish
Pages (from-to)1172-1174
Number of pages3
JournalObstetrics and Gynecology
Issue number5 PART 2
StatePublished - Nov 2004
Externally publishedYes


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