Trimethoprim sulphamethoxazole in neonatal Flavobacterium meningosepticum infection

N. Linder, S. H. Korman, F. Eyal, J. Michel

Research output: Contribution to journalArticlepeer-review

Abstract

During an outbreak of Flavobacterium meningosepticum septicaemia in a neonatal intensive care unit 9 infants were treated with intravenous trimethoprim sulphamethoxazole. Bacteriological cure was achieved in 8 patients; one infant died of massive intraventricular haemorrhage on the first day of treatment. Apart from prolonged persistence of pre-existing thrombocytopenia there was no evidence of side effects. Trimethoprim sulphamethoxazole should be considered in the treatment of neonatal F meningosepticum sepsis in view of its activity against this organism, good penetration of the blood brain barrier, and the absence of serious side effects.

Original languageEnglish
Pages (from-to)582-584
Number of pages3
JournalArchives of Disease in Childhood
Volume59
Issue number6
DOIs
StatePublished - 1984
Externally publishedYes

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