Trends in the incidence of type 1 diabetes among Jews and Arabs in Israel

Orit Blumenfeld, Rita Dichtiar, Tamy Shohat, Zvy Bistritzer, Marianna Rahmeal, Aharon Klar, Pnina Vardi, Ilana Koren, Alina German, Hussein Majdub, David Strich, Aaron Hanukoglu, Zohar Landau, Itamar Raz, David Zangen, David Gillis, Ram Weiss, Abdulsalam Abulibdeh, Carmit Avnon-Ziv, Yardena Tenenbaum-RakoverOsnat Admoni, Tal Almagor, Gadir Elias, Mari Nofi-Barhom, Anat Jaffe, Amnon Zung, Zvi Zadic, Ella Burundukov, Orit Pinhas-Hamiel, Chana Graf Bar-El, Kineret Mazor-Aronovitch, Rachel Frumkin-Ben-David, Naim Shehadeh, Amir Haddash, Orna Dally Gottfried, Moshe Phillip, Shlomit Shalitin, Liora Lazar, Liat De Vries, Revital Nimri, Yael Lebenthal, Ariel Tenenbaum, Rachel Frumkin, Josef Meirovitz, Tal Ben Ari, Tal Oron, Eran Mel, Nitzan Dror, Demil Sharon, Alon Farfel, Floris Levy-Khademi, Dalit Modan-Moses, Kineret Mazor-ronovitch, Yael Levy Shraga, Michal Ben-Ami, Yonatan Yeshayahu, Gertha Brill, Hedy Landau, Eli Hershkovitz, Neta Loewenthal, Alon Haim, Noami Weintrob, Ori Eyal, Lea Even

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To assess the trends in the incidence of type 1 diabetes between 1997 and 2010 among 0-17-yr-old Israeli Jews and Arabs compared with global trends. Methods: Data on children with newly diagnosed type 1 diabetes reported by pediatric endocrinologists from 19 medical centers to the Israel Center for Disease Control, as part of the National Diabetes Register. Results: During 1997-2010, 2857 Jews and 757 Arabs were diagnosed with type 1 diabetes. The average age-adjusted incidence among Jews was higher than Arabs [12.2 per 100 000, 95% confidence interval (CI) 10.5-14.2 and 8.9 per 100 000, 95% CI 7.5-10.7, p = 0.0001, respectively], however, the annual percent change was higher for Arabs compared with Jews (4.0 vs. 3.6%, p = 0.005, respectively). The mean age at diagnosis was similar for Jews and Arabs (9.6 ± 4.4 vs. 9.9 ± 4.4 yr, p = 0.08), and it remained stable during 1997-2010 in both ethnic groups (p = 0.6). In both Jews and Arabs the highest annual percent change was observed in younger children. It was 4.9% for children aged 5-9 yr and 10.7% for children aged 0-4 yr, respectively. There were no differences in the frequency of diabetic ketoacidosis (DKA) between Jews (39.9%) and Arabs (41.3%), (p = 0.5). Conclusion: Type 1 diabetes incidence of Jews and Arabs in Israel is increasing. The incidence is higher in Jews than in Arabs; however, the annual percent change is higher in Arabs than in Jews. In both Ethnic groups the incidence of type 1 diabetes is increasing especially among young children.

Original languageEnglish
Pages (from-to)422-427
Number of pages6
JournalPediatric Diabetes
Volume15
Issue number6
DOIs
StatePublished - Sep 2014
Externally publishedYes

Keywords

  • Incidence trend
  • Israeli jews and israeli arabs
  • Type 1 diabetes

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