Trends in the incidence of type 1 diabetes among Jews and Arabs in Israel

Orit Blumenfeld; Rita Dichtiar; Tamy Shohat; Zvy Bistritzer; Marianna Rahmeal; Aharon Klar; Pnina Vardi; Ilana Koren; Alina German; Hussein Majdub; David Strich; Aaron Hanukoglu; Zohar Landau; Itamar Raz; David Zangen; David Gillis; Ram Weiss; Abdulsalam Abulibdeh; Carmit Avnon-Ziv; Yardena Tenenbaum-Rakover; Osnat Admoni; Tal Almagor; Gadir Elias; Mari Nofi-Barhom; Anat Jaffe; Amnon Zung; Zvi Zadic; Ella Burundukov; Orit Pinhas-Hamiel; Chana Graf Bar-El; Kineret Mazor-Aronovitch; Rachel Frumkin-Ben-David; Naim Shehadeh; Amir Haddash; Orna Dally Gottfried; Moshe Phillip; Shlomit Shalitin; Liora Lazar; Liat De Vries; Revital Nimri; Yael Lebenthal; Ariel Tenenbaum; Rachel Frumkin; Josef Meirovitz; Tal Ben Ari; Tal Oron; Eran Mel; Nitzan Dror; Demil Sharon; Alon Farfel; Floris Levy-Khademi; Dalit Modan-Moses; Kineret Mazor-ronovitch; Yael Levy Shraga; Michal Ben-Ami; Yonatan Yeshayahu; Gertha Brill; Hedy Landau; Eli Hershkovitz; Neta Loewenthal; Alon Haim; Noami Weintrob; Ori Eyal; Lea Even

doi:10.1111/pedi.12101

Trends in the incidence of type 1 diabetes among Jews and Arabs in Israel

Orit Blumenfeld^*, Rita Dichtiar, Tamy Shohat, Zvy Bistritzer, Marianna Rahmeal, Aharon Klar, Pnina Vardi, Ilana Koren, Alina German, Hussein Majdub, David Strich, Aaron Hanukoglu, Zohar Landau, Itamar Raz, David Zangen, David Gillis, Ram Weiss, Abdulsalam Abulibdeh, Carmit Avnon-Ziv, Yardena Tenenbaum-RakoverOsnat Admoni, Tal Almagor, Gadir Elias, Mari Nofi-Barhom, Anat Jaffe, Amnon Zung, Zvi Zadic, Ella Burundukov, Orit Pinhas-Hamiel, Chana Graf Bar-El, Kineret Mazor-Aronovitch, Rachel Frumkin-Ben-David, Naim Shehadeh, Amir Haddash, Orna Dally Gottfried, Moshe Phillip, Shlomit Shalitin, Liora Lazar, Liat De Vries, Revital Nimri, Yael Lebenthal, Ariel Tenenbaum, Rachel Frumkin, Josef Meirovitz, Tal Ben Ari, Tal Oron, Eran Mel, Nitzan Dror, Demil Sharon, Alon Farfel, Floris Levy-Khademi, Dalit Modan-Moses, Kineret Mazor-ronovitch, Yael Levy Shraga, Michal Ben-Ami, Yonatan Yeshayahu, Gertha Brill, Hedy Landau, Eli Hershkovitz, Neta Loewenthal, Alon Haim, Noami Weintrob, Ori Eyal, Lea Even

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Objective: To assess the trends in the incidence of type 1 diabetes between 1997 and 2010 among 0-17-yr-old Israeli Jews and Arabs compared with global trends. Methods: Data on children with newly diagnosed type 1 diabetes reported by pediatric endocrinologists from 19 medical centers to the Israel Center for Disease Control, as part of the National Diabetes Register. Results: During 1997-2010, 2857 Jews and 757 Arabs were diagnosed with type 1 diabetes. The average age-adjusted incidence among Jews was higher than Arabs [12.2 per 100 000, 95% confidence interval (CI) 10.5-14.2 and 8.9 per 100 000, 95% CI 7.5-10.7, p = 0.0001, respectively], however, the annual percent change was higher for Arabs compared with Jews (4.0 vs. 3.6%, p = 0.005, respectively). The mean age at diagnosis was similar for Jews and Arabs (9.6 ± 4.4 vs. 9.9 ± 4.4 yr, p = 0.08), and it remained stable during 1997-2010 in both ethnic groups (p = 0.6). In both Jews and Arabs the highest annual percent change was observed in younger children. It was 4.9% for children aged 5-9 yr and 10.7% for children aged 0-4 yr, respectively. There were no differences in the frequency of diabetic ketoacidosis (DKA) between Jews (39.9%) and Arabs (41.3%), (p = 0.5). Conclusion: Type 1 diabetes incidence of Jews and Arabs in Israel is increasing. The incidence is higher in Jews than in Arabs; however, the annual percent change is higher in Arabs than in Jews. In both Ethnic groups the incidence of type 1 diabetes is increasing especially among young children.

Original language	English
Pages (from-to)	422-427
Number of pages	6
Journal	Pediatric Diabetes
Volume	15
Issue number	6
DOIs	https://doi.org/10.1111/pedi.12101
State	Published - Sep 2014
Externally published	Yes

Keywords

Incidence trend
Israeli jews and israeli arabs
Type 1 diabetes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/pedi.12101

Cite this

Blumenfeld, O., Dichtiar, R., Shohat, T., Bistritzer, Z., Rahmeal, M., Klar, A., Vardi, P., Koren, I., German, A., Majdub, H., Strich, D., Hanukoglu, A., Landau, Z., Raz, I., Zangen, D., Gillis, D., Weiss, R., Abulibdeh, A., Avnon-Ziv, C., ... Even, L. (2014). Trends in the incidence of type 1 diabetes among Jews and Arabs in Israel. Pediatric Diabetes, 15(6), 422-427. https://doi.org/10.1111/pedi.12101

@article{00088162ccc945a292462eabc191b382,

title = "Trends in the incidence of type 1 diabetes among Jews and Arabs in Israel",

abstract = "Objective: To assess the trends in the incidence of type 1 diabetes between 1997 and 2010 among 0-17-yr-old Israeli Jews and Arabs compared with global trends. Methods: Data on children with newly diagnosed type 1 diabetes reported by pediatric endocrinologists from 19 medical centers to the Israel Center for Disease Control, as part of the National Diabetes Register. Results: During 1997-2010, 2857 Jews and 757 Arabs were diagnosed with type 1 diabetes. The average age-adjusted incidence among Jews was higher than Arabs [12.2 per 100 000, 95% confidence interval (CI) 10.5-14.2 and 8.9 per 100 000, 95% CI 7.5-10.7, p = 0.0001, respectively], however, the annual percent change was higher for Arabs compared with Jews (4.0 vs. 3.6%, p = 0.005, respectively). The mean age at diagnosis was similar for Jews and Arabs (9.6 ± 4.4 vs. 9.9 ± 4.4 yr, p = 0.08), and it remained stable during 1997-2010 in both ethnic groups (p = 0.6). In both Jews and Arabs the highest annual percent change was observed in younger children. It was 4.9% for children aged 5-9 yr and 10.7% for children aged 0-4 yr, respectively. There were no differences in the frequency of diabetic ketoacidosis (DKA) between Jews (39.9%) and Arabs (41.3%), (p = 0.5). Conclusion: Type 1 diabetes incidence of Jews and Arabs in Israel is increasing. The incidence is higher in Jews than in Arabs; however, the annual percent change is higher in Arabs than in Jews. In both Ethnic groups the incidence of type 1 diabetes is increasing especially among young children.",

keywords = "Incidence trend, Israeli jews and israeli arabs, Type 1 diabetes",

author = "Orit Blumenfeld and Rita Dichtiar and Tamy Shohat and Zvy Bistritzer and Marianna Rahmeal and Aharon Klar and Pnina Vardi and Ilana Koren and Alina German and Hussein Majdub and David Strich and Aaron Hanukoglu and Zohar Landau and Itamar Raz and David Zangen and David Gillis and Ram Weiss and Abdulsalam Abulibdeh and Carmit Avnon-Ziv and Yardena Tenenbaum-Rakover and Osnat Admoni and Tal Almagor and Gadir Elias and Mari Nofi-Barhom and Anat Jaffe and Amnon Zung and Zvi Zadic and Ella Burundukov and Orit Pinhas-Hamiel and Bar-El, {Chana Graf} and Kineret Mazor-Aronovitch and Rachel Frumkin-Ben-David and Naim Shehadeh and Amir Haddash and {Dally Gottfried}, Orna and Moshe Phillip and Shlomit Shalitin and Liora Lazar and {De Vries}, Liat and Revital Nimri and Yael Lebenthal and Ariel Tenenbaum and Rachel Frumkin and Josef Meirovitz and {Ben Ari}, Tal and Tal Oron and Eran Mel and Nitzan Dror and Demil Sharon and Alon Farfel and Floris Levy-Khademi and Dalit Modan-Moses and Kineret Mazor-ronovitch and {Levy Shraga}, Yael and Michal Ben-Ami and Yonatan Yeshayahu and Gertha Brill and Hedy Landau and Eli Hershkovitz and Neta Loewenthal and Alon Haim and Noami Weintrob and Ori Eyal and Lea Even",

year = "2014",

month = sep,

doi = "10.1111/pedi.12101",

language = "אנגלית",

volume = "15",

pages = "422--427",

journal = "Pediatric Diabetes",

issn = "1399-543X",

publisher = "Blackwell Munksgaard",

number = "6",

}

Blumenfeld, O, Dichtiar, R, Shohat, T, Bistritzer, Z, Rahmeal, M, Klar, A, Vardi, P, Koren, I, German, A, Majdub, H, Strich, D, Hanukoglu, A , Landau, Z, Raz, I, Zangen, D, Gillis, D, Weiss, R, Abulibdeh, A, Avnon-Ziv, C, Tenenbaum-Rakover, Y, Admoni, O, Almagor, T, Elias, G, Nofi-Barhom, M, Jaffe, A, Zung, A, Zadic, Z, Burundukov, E, Pinhas-Hamiel, O, Bar-El, CG, Mazor-Aronovitch, K, Frumkin-Ben-David, R, Shehadeh, N, Haddash, A, Dally Gottfried, O, Phillip, M , Shalitin, S , Lazar, L , De Vries, L , Nimri, R , Lebenthal, Y, Tenenbaum, A, Frumkin, R, Meirovitz, J, Ben Ari, T , Oron, T, Mel, E, Dror, N, Sharon, D, Farfel, A, Levy-Khademi, F, Modan-Moses, D, Mazor-ronovitch, K, Levy Shraga, Y, Ben-Ami, M, Yeshayahu, Y, Brill, G, Landau, H, Hershkovitz, E, Loewenthal, N, Haim, A, Weintrob, N , Eyal, O & Even, L 2014, 'Trends in the incidence of type 1 diabetes among Jews and Arabs in Israel', Pediatric Diabetes, vol. 15, no. 6, pp. 422-427. https://doi.org/10.1111/pedi.12101

TY - JOUR

T1 - Trends in the incidence of type 1 diabetes among Jews and Arabs in Israel

AU - Blumenfeld, Orit

AU - Dichtiar, Rita

AU - Shohat, Tamy

AU - Bistritzer, Zvy

AU - Rahmeal, Marianna

AU - Klar, Aharon

AU - Vardi, Pnina

AU - Koren, Ilana

AU - German, Alina

AU - Majdub, Hussein

AU - Strich, David

AU - Hanukoglu, Aaron

AU - Landau, Zohar

AU - Raz, Itamar

AU - Zangen, David

AU - Gillis, David

AU - Weiss, Ram

AU - Abulibdeh, Abdulsalam

AU - Avnon-Ziv, Carmit

AU - Tenenbaum-Rakover, Yardena

AU - Admoni, Osnat

AU - Almagor, Tal

AU - Elias, Gadir

AU - Nofi-Barhom, Mari

AU - Jaffe, Anat

AU - Zung, Amnon

AU - Zadic, Zvi

AU - Burundukov, Ella

AU - Pinhas-Hamiel, Orit

AU - Bar-El, Chana Graf

AU - Mazor-Aronovitch, Kineret

AU - Frumkin-Ben-David, Rachel

AU - Shehadeh, Naim

AU - Haddash, Amir

AU - Dally Gottfried, Orna

AU - Phillip, Moshe

AU - Shalitin, Shlomit

AU - Lazar, Liora

AU - De Vries, Liat

AU - Nimri, Revital

AU - Lebenthal, Yael

AU - Tenenbaum, Ariel

AU - Frumkin, Rachel

AU - Meirovitz, Josef

AU - Ben Ari, Tal

AU - Oron, Tal

AU - Mel, Eran

AU - Dror, Nitzan

AU - Sharon, Demil

AU - Farfel, Alon

AU - Levy-Khademi, Floris

AU - Modan-Moses, Dalit

AU - Mazor-ronovitch, Kineret

AU - Levy Shraga, Yael

AU - Ben-Ami, Michal

AU - Yeshayahu, Yonatan

AU - Brill, Gertha

AU - Landau, Hedy

AU - Hershkovitz, Eli

AU - Loewenthal, Neta

AU - Haim, Alon

AU - Weintrob, Noami

AU - Eyal, Ori

AU - Even, Lea

PY - 2014/9

Y1 - 2014/9

N2 - Objective: To assess the trends in the incidence of type 1 diabetes between 1997 and 2010 among 0-17-yr-old Israeli Jews and Arabs compared with global trends. Methods: Data on children with newly diagnosed type 1 diabetes reported by pediatric endocrinologists from 19 medical centers to the Israel Center for Disease Control, as part of the National Diabetes Register. Results: During 1997-2010, 2857 Jews and 757 Arabs were diagnosed with type 1 diabetes. The average age-adjusted incidence among Jews was higher than Arabs [12.2 per 100 000, 95% confidence interval (CI) 10.5-14.2 and 8.9 per 100 000, 95% CI 7.5-10.7, p = 0.0001, respectively], however, the annual percent change was higher for Arabs compared with Jews (4.0 vs. 3.6%, p = 0.005, respectively). The mean age at diagnosis was similar for Jews and Arabs (9.6 ± 4.4 vs. 9.9 ± 4.4 yr, p = 0.08), and it remained stable during 1997-2010 in both ethnic groups (p = 0.6). In both Jews and Arabs the highest annual percent change was observed in younger children. It was 4.9% for children aged 5-9 yr and 10.7% for children aged 0-4 yr, respectively. There were no differences in the frequency of diabetic ketoacidosis (DKA) between Jews (39.9%) and Arabs (41.3%), (p = 0.5). Conclusion: Type 1 diabetes incidence of Jews and Arabs in Israel is increasing. The incidence is higher in Jews than in Arabs; however, the annual percent change is higher in Arabs than in Jews. In both Ethnic groups the incidence of type 1 diabetes is increasing especially among young children.

AB - Objective: To assess the trends in the incidence of type 1 diabetes between 1997 and 2010 among 0-17-yr-old Israeli Jews and Arabs compared with global trends. Methods: Data on children with newly diagnosed type 1 diabetes reported by pediatric endocrinologists from 19 medical centers to the Israel Center for Disease Control, as part of the National Diabetes Register. Results: During 1997-2010, 2857 Jews and 757 Arabs were diagnosed with type 1 diabetes. The average age-adjusted incidence among Jews was higher than Arabs [12.2 per 100 000, 95% confidence interval (CI) 10.5-14.2 and 8.9 per 100 000, 95% CI 7.5-10.7, p = 0.0001, respectively], however, the annual percent change was higher for Arabs compared with Jews (4.0 vs. 3.6%, p = 0.005, respectively). The mean age at diagnosis was similar for Jews and Arabs (9.6 ± 4.4 vs. 9.9 ± 4.4 yr, p = 0.08), and it remained stable during 1997-2010 in both ethnic groups (p = 0.6). In both Jews and Arabs the highest annual percent change was observed in younger children. It was 4.9% for children aged 5-9 yr and 10.7% for children aged 0-4 yr, respectively. There were no differences in the frequency of diabetic ketoacidosis (DKA) between Jews (39.9%) and Arabs (41.3%), (p = 0.5). Conclusion: Type 1 diabetes incidence of Jews and Arabs in Israel is increasing. The incidence is higher in Jews than in Arabs; however, the annual percent change is higher in Arabs than in Jews. In both Ethnic groups the incidence of type 1 diabetes is increasing especially among young children.

KW - Incidence trend

KW - Israeli jews and israeli arabs

KW - Type 1 diabetes

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DO - 10.1111/pedi.12101

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AN - SCOPUS:84906789889

SN - 1399-543X

VL - 15

SP - 422

EP - 427

JO - Pediatric Diabetes

JF - Pediatric Diabetes

IS - 6

ER -

Trends in the incidence of type 1 diabetes among Jews and Arabs in Israel

Abstract

Keywords

UN SDGs

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