TY - JOUR
T1 - Treatment with aspirin, NSAID, corticosteroids, and colchicine in acute and recurrent pericarditis
AU - Imazio, Massimo
AU - Adler, Yehuda
PY - 2013/5
Y1 - 2013/5
N2 - Empiric anti-inflammatory therapy for acute and recurrent pericarditis is warranted for viral and idiopathic cases that represent most cases of pericarditis in developed countries. For specific uncomplicated etiologies, such as systemic autoimmune diseases and postpericardiotomy syndromes, the same drugs are also indicated. Aspirin and non-steroidal anti-inflammatory drugs (NSAID) are mainstay of therapy with the possible adjunct of colchicine, especially for recurrences. Corticosteroids are a second choice for difficult cases requiring multi-drug therapies and specific medical conditions (i.e., specific cases with systemic autoimmune diseases, postpericardiotomy syndrome, and pregnancy). Medical therapy of pericarditis should be individualized as much as possible providing the attack dose every 8 h to ensure full daily control of symptoms and till remission and C-reactive protein normalization, and then tapering should be considered. The present paper will review current evidence for the treatment of acute and recurrent pericarditis with aspirin, NSAID, corticosteroids, and colchicine.
AB - Empiric anti-inflammatory therapy for acute and recurrent pericarditis is warranted for viral and idiopathic cases that represent most cases of pericarditis in developed countries. For specific uncomplicated etiologies, such as systemic autoimmune diseases and postpericardiotomy syndromes, the same drugs are also indicated. Aspirin and non-steroidal anti-inflammatory drugs (NSAID) are mainstay of therapy with the possible adjunct of colchicine, especially for recurrences. Corticosteroids are a second choice for difficult cases requiring multi-drug therapies and specific medical conditions (i.e., specific cases with systemic autoimmune diseases, postpericardiotomy syndrome, and pregnancy). Medical therapy of pericarditis should be individualized as much as possible providing the attack dose every 8 h to ensure full daily control of symptoms and till remission and C-reactive protein normalization, and then tapering should be considered. The present paper will review current evidence for the treatment of acute and recurrent pericarditis with aspirin, NSAID, corticosteroids, and colchicine.
KW - Aspirin
KW - Colchicine
KW - Corticosteroids
KW - Non-steroidal anti-inflammatory drugs
KW - Pericarditis
KW - Therapy
UR - http://www.scopus.com/inward/record.url?scp=84877833091&partnerID=8YFLogxK
U2 - 10.1007/s10741-012-9328-9
DO - 10.1007/s10741-012-9328-9
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C2 - 22661042
AN - SCOPUS:84877833091
SN - 1382-4147
VL - 18
SP - 355
EP - 360
JO - Heart Failure Reviews
JF - Heart Failure Reviews
IS - 3
ER -