Treatment of verrucous epidermal nevus: Experience with 71 cases

M. Lapidoth, H. Israeli, D. Ben Amitai, S. Halachmi

Research output: Contribution to journalArticlepeer-review


Objective: The aim of this study was to evaluate the clinical results of 71 cases with verrucous epidermal nevus (VEN) treated by cryotherapy or CO 2 laser. Methods: The files and photographs of patients with VEN who were treated in the laser unit of a tertiary hospital between January 2005 and December 2011 were evaluated. Pretreatment and 12-month follow-up photographs were evaluated using a 5-point scale: 'excellent' (75-100% clearance), 'good' (50-75% clearance), 'fair' (25-50% clearance), 'poor' (<25% clearance) or 'worse'. Results: Of 71 patients, 62 responded well to cryotherapy alone, and 9 facial VEN required CO2 laser treatment. Small VEN required relatively few treatments (mean 3.4) with 90% scoring 'excellent' and 10% scoring 'good'. Larger VEN required more treatments (mean 7.4) and did not respond as well, with 71% scoring 'excellent', 14% scoring 'good' and 14% scoring 'fair'. Conclusion: Our experience suggests that cryotherapy is the ideal treatment for small facial VEN, while ablation by CO2 laser should be considered an option for resistant facial lesions.

Original languageEnglish
Pages (from-to)342-346
Number of pages5
Issue number4
StatePublished - Sep 2013


  • CO laser
  • Cryotherapy
  • Epidermal nevus
  • Treatment


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