Treatment of systemic lupus erythematosus and antiphospholipid syndrome: From experimental models to patients’ bedside

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Abstract

Animal models are of great value in the evaluation of novel and experimental treatments that cannot be tested directly on patients. In this article, we summarize the spectrum of murine models for systemic lupus erythematosus and antiphospholipid syndrome, focusing on animal models based on idiotypic immunization. Several therapeutic modalities that have been tested in those models had promising potential for application in human patients.

Original languageEnglish
Pages (from-to)355-361
Number of pages7
JournalInternational Archives of Allergy and Immunology
Volume111
Issue number4
DOIs
StatePublished - 1996

Keywords

  • Antiphospholipid syndrome
  • Autoimmunity
  • Idiotypes
  • Systemic lupus erythematosus

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