TY - JOUR
T1 - Treatment of severe cholestasis in neonatal Dubin-Johnson syndrome with ursodeoxycholic acid
AU - Regev, Rivka H.
AU - Stolar, Orit
AU - Raz, Aryeh
AU - Dolfin, Tzipora
PY - 2002
Y1 - 2002
N2 - We report a case of Dubin-Johnson Syndrome in a neonate presenting with severe direct hyperbilirubinemia, which failed to respond to phenobarbital treatment. Ursodeoxycholic Acid added to therapy was well tolerated, and resulted in declining bilirubin concentration. We suggest ursodeoxycholic acid in treatment for Dubin-Johnson Syndrome with severe direct hyperbilirubinemia presenting in the neonatal age.
AB - We report a case of Dubin-Johnson Syndrome in a neonate presenting with severe direct hyperbilirubinemia, which failed to respond to phenobarbital treatment. Ursodeoxycholic Acid added to therapy was well tolerated, and resulted in declining bilirubin concentration. We suggest ursodeoxycholic acid in treatment for Dubin-Johnson Syndrome with severe direct hyperbilirubinemia presenting in the neonatal age.
KW - Cholestatic jaundice
KW - Neonatal Dubin-Johnson syndrome
KW - Ursodeoxycholic acid
UR - http://www.scopus.com/inward/record.url?scp=0036117708&partnerID=8YFLogxK
U2 - 10.1515/JPM.2002.025
DO - 10.1515/JPM.2002.025
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:0036117708
SN - 0300-5577
VL - 30
SP - 185
EP - 187
JO - Journal of Perinatal Medicine
JF - Journal of Perinatal Medicine
IS - 2
ER -