Treatment of pure red-cell aplasia following major ABO-mismatched T-cell-depleted bone marrow transplantation - Two case reports with successful response to plasmapheresis

R. Or, E. Naparstek, N. Mani, S. Slavin

Research output: Contribution to journalArticlepeer-review

Abstract

Major ABO-mismatched bone marrow transplantation (BMT) may be accompanied by red-cell haemolysis, but pure red-cell aplasia following BMT is a rare complication. Two cases of transient pure red-cell aplasia following T-lymphocyte-depleted BMT for a period of >20 weeks are described, both of which responded to one cycle of plasmapheresis. The prompt response of the two patients described with red-cell aplasia with no evidence of haemolysis suggests that plasmapheresis may be considered in such clinical situations as a first treatment of choice before attempting more complex modes of therapy.

Original languageEnglish
Pages (from-to)99-102
Number of pages4
JournalTransplant International
Volume4
Issue number2
DOIs
StatePublished - Jun 1991
Externally publishedYes

Keywords

  • ABO mismatch
  • ABO mismatch, in bone marrow tranplantation
  • Bone marrow transplantation
  • Red blood cell aplasia, in bone marrow transplantation

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