Treatment of interstitial pregnancy with methotrexate via hysteroscopy

M. Goldenberg*, D. Bider, G. Oelsner, D. Admon, S. Mashiach

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We present a case in which treatment of interstitial pregnancy with local MTX administration was performed successfully through hysteroscopic vision, without the need to operate. Decreased gestational sac dimension and increased or low β-hCG level (<1,400 mIU/mL) facilitates the success rate. The follow-up showed disappearance of the gestational sac and decrease of β- hCG levels to <10 mIU/mL. We conclude that local MTX administration via hysteroscopy after tubal ostium visualization is feasible. The procedure should be considered in women during the reproductive age, especially in rare cases of interstitial pregnancy.

Original languageEnglish
Pages (from-to)1234-1236
Number of pages3
JournalFertility and Sterility
Issue number6
StatePublished - 1992
Externally publishedYes


  • Interstitial pregnancy
  • hysteroscopy
  • methotrexate


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