TY - JOUR
T1 - Treatment of high-grade squamous intraepithelial lesions
T2 - A "see and treat" versus a three-step approach
AU - Sadan, Oscar
AU - Yarden, Havazelet
AU - Schejter, Eduardo
AU - Bilevsky, Efi
AU - Bachar, Rachel
AU - Lurie, Samuel
PY - 2007/3
Y1 - 2007/3
N2 - Objective: The study's subject was to examine the correlation between histologic findings in patients with high-grade squamous intraepithelial lesion (HGSIL) who have undergone loop electrosurgical excisional procedure (LEEP) with and without prior colposcopically directed biopsy. Studydesign: This retrospective study included 144 patients with cytologic HGSIL, of which 62 were treated by a three-step protocol, in which LEEP was performed only if the colposcopically directed cervical biopsies were positive (CIN II-III), and 82 women who were treated by "see and treat" protocol, in which LEEP was immediately performed if colposcopy was suggestive of CIN II or III lesions. Results: There were no differences in the final histological findings between the groups. Conclusions: The colposcopically directed LEEP after a HGSIL on PAP-smear may reduce the time interval between diagnosis and treatment with a similar accuracy of diagnosis compared to the standard three-step protocol.
AB - Objective: The study's subject was to examine the correlation between histologic findings in patients with high-grade squamous intraepithelial lesion (HGSIL) who have undergone loop electrosurgical excisional procedure (LEEP) with and without prior colposcopically directed biopsy. Studydesign: This retrospective study included 144 patients with cytologic HGSIL, of which 62 were treated by a three-step protocol, in which LEEP was performed only if the colposcopically directed cervical biopsies were positive (CIN II-III), and 82 women who were treated by "see and treat" protocol, in which LEEP was immediately performed if colposcopy was suggestive of CIN II or III lesions. Results: There were no differences in the final histological findings between the groups. Conclusions: The colposcopically directed LEEP after a HGSIL on PAP-smear may reduce the time interval between diagnosis and treatment with a similar accuracy of diagnosis compared to the standard three-step protocol.
KW - CIN
KW - Colposocopy
KW - HGSIL
UR - http://www.scopus.com/inward/record.url?scp=33847143214&partnerID=8YFLogxK
U2 - 10.1016/j.ejogrb.2005.12.025
DO - 10.1016/j.ejogrb.2005.12.025
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:33847143214
SN - 0301-2115
VL - 131
SP - 73
EP - 75
JO - European Journal of Obstetrics and Gynecology and Reproductive Biology
JF - European Journal of Obstetrics and Gynecology and Reproductive Biology
IS - 1
ER -