Treatment of high-grade squamous intraepithelial lesions: A "see and treat" versus a three-step approach

Oscar Sadan, Havazelet Yarden, Eduardo Schejter, Efi Bilevsky, Rachel Bachar, Samuel Lurie*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Objective: The study's subject was to examine the correlation between histologic findings in patients with high-grade squamous intraepithelial lesion (HGSIL) who have undergone loop electrosurgical excisional procedure (LEEP) with and without prior colposcopically directed biopsy. Studydesign: This retrospective study included 144 patients with cytologic HGSIL, of which 62 were treated by a three-step protocol, in which LEEP was performed only if the colposcopically directed cervical biopsies were positive (CIN II-III), and 82 women who were treated by "see and treat" protocol, in which LEEP was immediately performed if colposcopy was suggestive of CIN II or III lesions. Results: There were no differences in the final histological findings between the groups. Conclusions: The colposcopically directed LEEP after a HGSIL on PAP-smear may reduce the time interval between diagnosis and treatment with a similar accuracy of diagnosis compared to the standard three-step protocol.

Original languageEnglish
Pages (from-to)73-75
Number of pages3
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
Issue number1
StatePublished - Mar 2007


  • CIN
  • Colposocopy


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