Treatment of airway obstruction by metallic stents in infants and children

Objective: The internal metallic stent is a relatively new and controversial method for the treatment of airway collapse in infants and children. The study examined the outcomes of this treatment in a large group of patients and defined clear indications for airway stenting. Methods: A retrospective review was conducted of 32 patients in whom 42 stents were inserted. The patients were divided into three groups with respect to the stented segment: group A, trachea (n = 14); group B, bronchi (n = 16); and group C, trachea and bronchi (n = 2). Results: In 30 cases, there was immediate improvement of respiratory obstruction, and 23 patients could be weaned, at least temporarily, from ventilation. Excessive granulation developed after the stenting in 26 patients. In 6 patients, all in group A, the granulation and inflammatory reaction generated severe airway obstruction, necessitating thoracotomy in 2 cases. One patient died of airway obstruction, and another died during the attempt to remove the stent; both were in group A. Stents placed for 2 to 72 months (mean 8.7 months) have now been removed in 11 patients. Six children are alive and well with stents in place, 2 from group A and 4 from group B. Fifteen patients died during the follow-up period; in 13 cases, death was related to the associated disease. Conclusion: The use of metallic stents, especially in the trachea, is associated with a high rate of complications. Granulation tissue, which often develops after stenting, is a major concern. Removal of the stents is arduous and carries a high risk of complications. The use of stents should be restricted to the limited situations in which conventional initial therapy has failed.