Trazodone and mirtazapine: A possible opioid involvement in their use (at low dose) for sleep?

Keyphrases

• Opioids 100%
• Mirtazapine 100%
• Trazodone 100%
• Antinociceptive 80%
• Antidepressants 60%
• Noradrenergic 40%
• Serotonergic System 40%
• Adrenoceptors 40%
• Opioid Receptor Subtypes 40%
• Antagonism 20%
• Serotonin 20%
• Mechanism of Action 20%
• Hot Plate 20%
• Benzodiazepines 20%
• Spontaneous Excitatory Postsynaptic Current (sEPSC) 20%
• Analgesia 20%
• Naloxone 20%
• Opioid Agonist 20%
• Opioid System 20%
• Therapeutic Agents 20%
• Medication Use 20%
• Sedative 20%
• Specific Inhibitor 20%
• 5-hydroxytryptamine 20%
• Amitriptyline 20%
• Hetero 20%
• ICR Mice 20%
• Relative Contraindications 20%
• Mechanisms of Antinociception 20%
• α2-adrenoceptor 20%
• 5-HT1A 20%
• Sedative-hypnotic 20%
• Antidepressant Mechanism 20%
• μ-opioid Receptor 20%
• Serotonergic Agonists 20%
• Non-benzodiazepine 20%
• Noradrenergic Receptors 20%
• Insomnia Treatment 20%
• Kappa Opioid Receptor 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Trazodone 100%
• Mirtazapine 100%
• Antidepressant 80%
• Opiate Receptor 40%
• Receptor Subtype 40%
• Adrenergic Receptor 40%
• Serotonin 20%
• Naloxone 20%
• Opiate Agonist 20%
• μ-Opioid Receptor 20%
• Kappa Opiate Receptor 20%
• Amitriptyline 20%
• Institute for Cancer Research Mouse 20%
• Hypnotic Sedative Agent 20%
• Alpha 2 Adrenergic Receptor 20%
• Serotonin Agonist 20%
• Nonbenzodiazepine 20%
• Alpha Adrenergic Receptor 20%
• Alpha Adrenergic Receptor Stimulating Agent 20%
• Antinociception 20%
• Serotonin Receptor 20%

Neuroscience

• Trazodone 100%
• Mirtazapine 100%
• Antidepressant 80%
• Serotonergic 40%
• Receptor Subtype 40%
• Adrenergic Receptor 40%
• Serotonin 20%
• Synaptic Transmission 20%
• Agonist 20%
• Naloxone 20%
• μ-Opioid Receptor 20%
• Kappa Opiate Receptor 20%
• 5-HT Receptor 20%
• Amitriptyline 20%
• Alpha Adrenergic Receptor 20%
• Nonbenzodiazepine 20%
• Hypnotic 20%
• Alpha-2 Adrenergic Receptor 20%