Transport effects in biochip sensors with redox cycling amplification

Tali Dotan, Michael Nazarenko, Yuval Atiya, Yosi Shacham-Diamand*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We report a study of transport effects on a microfluidic sensor-chip in which electrochemical sensing is amplified by redox cycling using an interdigitated electrode array (IDA). A full three-dimensional simulation-based model and a simple one-dimensional model for the transition velocity between the two regimes is presented. These models indicate that there exist two dominant regimes: one which is limited by redox cycling diffusion—a unique feature of IDAs— and another which is limited by convection and has dominant flow effects. The transition velocity between the two sensing regimes was found to be vflow[[Formula presented]]=[Formula presented]+0.04 which is similar to the prediction of vflow∝[Formula presented], obtained from the one-dimensional model.

Original languageEnglish
Article number142520
JournalElectrochimica Acta
StatePublished - 10 Aug 2023


  • Biosensors
  • Finite element analysis simulation
  • Interdigitated electrode array
  • Mass transport
  • Redox cycling


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