Transient severe metastatic calcification in acute renal failure

Daniel Landau*, Hanna Krymko, Hanna Shalev, Svetlana Agronovich

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Metastatic calcification, a known complication of prolonged end-stage renal disease, is herein described for the first time in a 10-month-old boy with acute renal failure, manifesting as a painful and swollen arm. Imaging revealed diffuse calcification and technetium-99 methylene diphosphonate (99Tc-MDP) uptake around the humerus and axilla. Calcium and vitamin D restriction, followed by intravenous administration of sodium thiosulfate caused a full symptomatic, radio- and scintigraphic improvement.

Original languageEnglish
Pages (from-to)607-611
Number of pages5
JournalPediatric Nephrology
Issue number4
StatePublished - Apr 2007
Externally publishedYes


  • Alfacalcidol
  • Calcific uremic arteriolopathy
  • Hemolytic uremic syndrome
  • Peritoneal dialysis
  • Radionuclide imaging
  • Sodium thiosulfate


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