Transient renal insufficiency following dipyrone overdose

Ibrahim Abu-Kishk, Michael Goldman, Yair Mordish, Matitiahu Berkovitch, Eran Kozer

Research output: Contribution to journalArticlepeer-review


Aim: To describe the incidence of acute renal insufficiency after dipyrone overdose in children. Methods: The medical records of all patients ≤18 years of age during a 3-year period presenting at Assaf Harofeh Medical Center due to toxic exposure were retrospectively reviewed. Patients suffering from dipyrone overdose were compared with all the other patients. Results: 235 cases were included in the fi nal analysis. Of these, 26 (11%) patients were exposed to dipyrone (median age 15 years). Three of the 26 patients (12%) had transient non-oliguric renal insuffi ciency. One other patient who did not receive dipyrone also developed transient renal insuffi ciency. Conclusions: Dipyrone overdose is frequent and may cause acute non-oliguric renal insuffi ciency. Renal function should be monitored in such patients.

Original languageEnglish
Pages (from-to)233-234
Number of pages2
JournalArchives of Disease in Childhood
Issue number3
StatePublished - Mar 2010
Externally publishedYes


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