Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity

Keyphrases

• Transgenic Mice 100%
• 6-hydroxydopamine (6-OHDA) 100%
• B-cell Lymphoma 2 (Bcl-2) 100%
• Neurotoxicity 100%
• 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 100%
• Neurotoxin 80%
• Cell Death 40%
• Gene Therapy 20%
• Neurodegenerative Diseases 20%
• In the Wild 20%
• Striatum 20%
• Dopaminergic Neurons 20%
• Overexpression 20%
• Overexpressing 20%
• Wild Mice 20%
• Dose Effect 20%
• Primary Culture 20%
• Oncogene 20%
• Dopamine Level 20%
• Normal Brain Development 20%
• Neuronal Survival 20%
• Neuronal Cell Death 20%
• Growth Factor Deprivation 20%
• Cytotoxic Drugs 20%
• Glutathione Peroxidase (GSH-Px) 20%
• Neuronal Apoptosis 20%
• Striatal Dopamine Level 20%
• MPP+ 20%
• Neuron-specific Enolase 20%
• Neuroprotective Genes 20%
• Drug Factors 20%
• Heterozygous Mice 20%
• Neocortical Neurons 20%

Neuroscience

• Oxidopamine 100%
• Bcl-2 100%
• Neurotoxicity 100%
• Tetrahydropyridine 100%
• Neurotoxin 80%
• Cell Death 40%
• Dopaminergic 20%
• Neuroprotective Agent 20%
• Striatum 20%
• Brain Development 20%
• Dopaminergic Neuron 20%
• Promoter Region 20%
• Growth Factor 20%
• Neurodegenerative Disorder 20%
• Neuronal Cell Death 20%
• Primary Culture 20%
• Proto Oncogene 20%
• Neuroapoptosis 20%
• Glutathione 20%
• MPP+ 20%
• Neuron-Specific Enolase 20%