TY - JOUR
T1 - Transfer of six or more embryos improves success rates in patients with repeated in vitro fertilization failures
AU - Azem, F.
AU - Yaron, Y.
AU - Amit, A.
AU - Yovel, I.
AU - Barak, Y.
AU - Peyser, M. R.
AU - David, M. P.
AU - Lessing, J. B.
PY - 1995
Y1 - 1995
N2 - Objective: To examine the results of six or more embryos transferred to patients whose IVF-ET cycles repeatedly met with failure. Design: Prospective clinical evaluation of pregnancy rates and pregnancy outcome. Setting: IVF- ET Unit. Patients: Seventy-two IVF patients who had failed at least four previous IVF cycles. Interventions: Forty-one patients (group A) received six or more embryos, and 31 patients (group B) chose to receive five embryos. Main Outcome Measures: Per embryo implantation rate, pregnancy rate, multiple pregnancies, and outcome were evaluated. Results: With the transfer of six or more embryos, the pregnancy rate was significantly higher than with the transfer of five embryos (56% versus 29%, respectively). This was associated with a slight, but insignificant, increase in multiple gestations. No difference in pregnancy outcome was noted among the groups. Conclusions: Patients who have had repeated IVF failures may have higher pregnancy rates if six or more embryos are transferred in subsequent cycles.
AB - Objective: To examine the results of six or more embryos transferred to patients whose IVF-ET cycles repeatedly met with failure. Design: Prospective clinical evaluation of pregnancy rates and pregnancy outcome. Setting: IVF- ET Unit. Patients: Seventy-two IVF patients who had failed at least four previous IVF cycles. Interventions: Forty-one patients (group A) received six or more embryos, and 31 patients (group B) chose to receive five embryos. Main Outcome Measures: Per embryo implantation rate, pregnancy rate, multiple pregnancies, and outcome were evaluated. Results: With the transfer of six or more embryos, the pregnancy rate was significantly higher than with the transfer of five embryos (56% versus 29%, respectively). This was associated with a slight, but insignificant, increase in multiple gestations. No difference in pregnancy outcome was noted among the groups. Conclusions: Patients who have had repeated IVF failures may have higher pregnancy rates if six or more embryos are transferred in subsequent cycles.
KW - IVF-ET
KW - repeated failure
UR - http://www.scopus.com/inward/record.url?scp=0028950404&partnerID=8YFLogxK
U2 - 10.1016/S0015-0282(16)57545-1
DO - 10.1016/S0015-0282(16)57545-1
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AN - SCOPUS:0028950404
SN - 0015-0282
VL - 63
SP - 1043
EP - 1046
JO - Fertility and Sterility
JF - Fertility and Sterility
IS - 5
ER -