Towards Alzheimer's disease vaccination.

Research output: Contribution to journalReview articlepeer-review


Active and passive immunization against fibrillar beta-amyloid of various mice models of Alzheimer's disease leads to the disaggregation and inhibition of plaque formation. Preliminary results showing improved behaviour and memory function obtained after administration of anti-beta-amyloid vaccines to transgenic mice encourage these and related approaches for testing in the treatment and prevention of Alzheimer's disease.

Original languageEnglish
Pages (from-to)85-92
Number of pages8
JournalMini-Reviews in Medicinal Chemistry
Issue number1
StatePublished - Feb 2002


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