Towards a personalized multi-domain digital neurophenotyping model for the detection and treatment of mood trajectories

Yaron Sela, Lorena Santamaria, Yair Amichai-Hamburge, Victoria Leong*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The commercial availability of many real-life smart sensors, wearables, and mobile apps provides a valuable source of information about a wide range of human behavioral, physiological, and social markers that can be used to infer the user’s mental state and mood. However, there are currently no commercial digital products that integrate these psychosocial metrics with the realtime measurement of neural activity. In particular, electroencephalography (EEG) is a wellvalidated and highly sensitive neuroimaging method that yields robust markers of mood and affective processing, and has been widely used in mental health research for decades. The integration of wearable neuro-sensors into existing multimodal sensor arrays could hold great promise for deep digital neurophenotyping in the detection and personalized treatment of mood disorders. In this paper, we propose a multi-domain digital neurophenotyping model based on the socioecological model of health. The proposed model presents a holistic approach to digital mental health, leveraging recent neuroscientific advances, and could deliver highly personalized diagnoses and treatments. The technological and ethical challenges of this model are discussed.

Original languageEnglish
Article number5781
Pages (from-to)1-9
Number of pages9
JournalSensors
Volume20
Issue number20
DOIs
StatePublished - 2 Oct 2020
Externally publishedYes

Keywords

  • Digital phenotyping
  • Dual-EEG
  • Mood disorders
  • Neurosensors

Fingerprint

Dive into the research topics of 'Towards a personalized multi-domain digital neurophenotyping model for the detection and treatment of mood trajectories'. Together they form a unique fingerprint.

Cite this