Total leucoderma: A rare manifestation of cutaneous chronic graft-versus-host disease

A. Nagler, M. A. Goldenhersh, F. Levi-Schaffer, J. C. Bystryn, S. N. Klaus

Research output: Contribution to journalArticlepeer-review

Abstract

We describe a 14-year-old boy who developed total leucoderma during the course of chronic graft-versus-host disease, which developed after allogeneic bone marrow transplantation. Skin biopsy and dihydroxy-phenylalanine staining revealed a total absence of melanocytes from the epidermis. Cytotoxic anti-melanocyte antibodies were found in the patient's serum, and this probably explains the development of the leucoderma.

Original languageEnglish
Pages (from-to)780-783
Number of pages4
JournalBritish Journal of Dermatology
Volume134
Issue number4
DOIs
StatePublished - 1996
Externally publishedYes

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