Total hip arthroplasty in patients with Down's syndrome

Yona Kosashvili; Drew Taylor; David Backstein; Oleg Safir; Boaz Liberman; Dror Lakstein; Allan Gross

doi:10.1007/s00264-010-1030-8

Total hip arthroplasty in patients with Down's syndrome

Yona Kosashvili^*, Drew Taylor, David Backstein, Oleg Safir, Boaz Liberman, Dror Lakstein, Allan Gross

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Patients with Down's syndrome (DS) have an increased incidence of coxarthrosis which may become symptomatic with prolonged life expectancy. We present seven consecutive patients (nine hips) with DS who had primary total hip arthroplasty (THA). Average clinical and radiological follow-up was 9.9±6.4 years (range 2-22.25). Harris hip scores (HHS) improved significantly (p<0.01) from 41.1 (range 18.5-65) to 80.2 (range 67.5-91) at latest follow-up. Two patients required revision arthroplasty for stem loosening at 16 (osteolysis) and six years (trauma) following THA, respectively. Six of the THAs required a constrained liner. No dislocations or deep infections were encountered. We contend that THA is a reliable surgical intervention in patients with DS and may be performed in symptomatic patients.

Original language	English
Pages (from-to)	661-666
Number of pages	6
Journal	International Orthopaedics
Volume	35
Issue number	5
DOIs	https://doi.org/10.1007/s00264-010-1030-8
State	Published - May 2011
Externally published	Yes

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abstract = "Patients with Down's syndrome (DS) have an increased incidence of coxarthrosis which may become symptomatic with prolonged life expectancy. We present seven consecutive patients (nine hips) with DS who had primary total hip arthroplasty (THA). Average clinical and radiological follow-up was 9.9±6.4 years (range 2-22.25). Harris hip scores (HHS) improved significantly (p<0.01) from 41.1 (range 18.5-65) to 80.2 (range 67.5-91) at latest follow-up. Two patients required revision arthroplasty for stem loosening at 16 (osteolysis) and six years (trauma) following THA, respectively. Six of the THAs required a constrained liner. No dislocations or deep infections were encountered. We contend that THA is a reliable surgical intervention in patients with DS and may be performed in symptomatic patients.",

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AU - Kosashvili, Yona

AU - Taylor, Drew

AU - Backstein, David

AU - Safir, Oleg

AU - Liberman, Boaz

AU - Lakstein, Dror

AU - Gross, Allan

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AB - Patients with Down's syndrome (DS) have an increased incidence of coxarthrosis which may become symptomatic with prolonged life expectancy. We present seven consecutive patients (nine hips) with DS who had primary total hip arthroplasty (THA). Average clinical and radiological follow-up was 9.9±6.4 years (range 2-22.25). Harris hip scores (HHS) improved significantly (p<0.01) from 41.1 (range 18.5-65) to 80.2 (range 67.5-91) at latest follow-up. Two patients required revision arthroplasty for stem loosening at 16 (osteolysis) and six years (trauma) following THA, respectively. Six of the THAs required a constrained liner. No dislocations or deep infections were encountered. We contend that THA is a reliable surgical intervention in patients with DS and may be performed in symptomatic patients.

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Total hip arthroplasty in patients with Down's syndrome

Abstract

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