Topical treatment with 1% sodium cromoglycate in pyoderma gangrenosum

A. Tamir, M. Landau, S. Brenner

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Pyoderma gangrenosum is an uncommon skin disease usually treated with systemic drugs, most frequently corticosteroids. Isolated topical treatment is usually considered unsatisfactory. Objective: To evaluate the effect of topical 1% sodium cromoglycate solution on pyoderma gangrenosum in 5 patients 25—30 years of age. Methods: 5 patients, including 2 under systemic steroid treatment, hospitalized in our department from 1992 to 1993 because of pyoderma gangrenosum, were treated with topical 1% sodium cromoglycate solution. Systemic corticosteroids were further added in 2 patients whose initial improvement was inadequate. Results: Initial improvement was noted in all 5 patients after 3—7 days of sodium cromoglycate treatment. Complete healing of the ulcers occurred within 5—8 weeks. Conclusions: Topical treatment with sodium cromoglycate can be effective as adjunctive or sole treatment in pyoderma gangrenosum.

Original languageEnglish
Pages (from-to)252-254
Number of pages3
JournalDermatology
Volume192
Issue number3
DOIs
StatePublished - Jan 1996

Keywords

  • Pyoderma gangrenosum
  • Sodium cromoglycate
  • Topical treatment

Fingerprint

Dive into the research topics of 'Topical treatment with 1% sodium cromoglycate in pyoderma gangrenosum'. Together they form a unique fingerprint.

Cite this