Topical ophthalmic amethocaine alleviates trigeminal neuralgia pain

Silviu Brill; Ron Ben-Abraham; Itay Goor-Aryeh

doi:10.2147/LRA.S14281

Topical ophthalmic amethocaine alleviates trigeminal neuralgia pain

Silviu Brill^*, Ron Ben-Abraham, Itay Goor-Aryeh

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Background: Trigeminal neuralgia (TGN) is a challenging pain syndrome. Aim: To test the effectiveness of local instillation of ophthalmic solution of amethocaine in relieving the pain of TGN. Methods: We performed an open-label prospective study in 40 consecutive currently treated patients suffering from TGN with a reported visual analog scale (VAS).8 (severe pain). The patients received two drops of amethocaine 1% instilled on the cornea ipsilateral to the painful side. Pain score assessment using VAS was recorded pre- and post-treatment. Results: A total of 32 (80%) patients reported a significant reduction in pain 10 minutes after drops instillation as compared with pre-treatment pain score. Pre-treatment VAS score was 8.53 ± 0.6 as compared with 4.78 ± 1.83 post-amethocaine treatments (P, 0.00001). Conclusion: Topical ophthalmic instillation of amethocaine 1% can be considered as an immediate effective method for pain paroxysm of TGN.

Original language	English
Pages (from-to)	155-157
Number of pages	3
Journal	Local and Regional Anesthesia
Volume	3
Issue number	1
DOIs	https://doi.org/10.2147/LRA.S14281
State	Published - 2010
Externally published	Yes

Keywords

Amethocaine
Ophthalmic
Pain
Trigeminal neuralgia

Access to Document

10.2147/LRA.S14281

Cite this

@article{2cec60cb5b7e4d2d9baa2259007fec82,

title = "Topical ophthalmic amethocaine alleviates trigeminal neuralgia pain",

abstract = "Background: Trigeminal neuralgia (TGN) is a challenging pain syndrome. Aim: To test the effectiveness of local instillation of ophthalmic solution of amethocaine in relieving the pain of TGN. Methods: We performed an open-label prospective study in 40 consecutive currently treated patients suffering from TGN with a reported visual analog scale (VAS).8 (severe pain). The patients received two drops of amethocaine 1% instilled on the cornea ipsilateral to the painful side. Pain score assessment using VAS was recorded pre- and post-treatment. Results: A total of 32 (80%) patients reported a significant reduction in pain 10 minutes after drops instillation as compared with pre-treatment pain score. Pre-treatment VAS score was 8.53 ± 0.6 as compared with 4.78 ± 1.83 post-amethocaine treatments (P, 0.00001). Conclusion: Topical ophthalmic instillation of amethocaine 1% can be considered as an immediate effective method for pain paroxysm of TGN.",

keywords = "Amethocaine, Ophthalmic, Pain, Trigeminal neuralgia",

author = "Silviu Brill and Ron Ben-Abraham and Itay Goor-Aryeh",

year = "2010",

doi = "10.2147/LRA.S14281",

language = "אנגלית",

volume = "3",

pages = "155--157",

journal = "Local and Regional Anesthesia",

issn = "1178-7112",

publisher = "Dove Medical Press Ltd.",

number = "1",

}

TY - JOUR

T1 - Topical ophthalmic amethocaine alleviates trigeminal neuralgia pain

AU - Brill, Silviu

AU - Ben-Abraham, Ron

AU - Goor-Aryeh, Itay

PY - 2010

Y1 - 2010

N2 - Background: Trigeminal neuralgia (TGN) is a challenging pain syndrome. Aim: To test the effectiveness of local instillation of ophthalmic solution of amethocaine in relieving the pain of TGN. Methods: We performed an open-label prospective study in 40 consecutive currently treated patients suffering from TGN with a reported visual analog scale (VAS).8 (severe pain). The patients received two drops of amethocaine 1% instilled on the cornea ipsilateral to the painful side. Pain score assessment using VAS was recorded pre- and post-treatment. Results: A total of 32 (80%) patients reported a significant reduction in pain 10 minutes after drops instillation as compared with pre-treatment pain score. Pre-treatment VAS score was 8.53 ± 0.6 as compared with 4.78 ± 1.83 post-amethocaine treatments (P, 0.00001). Conclusion: Topical ophthalmic instillation of amethocaine 1% can be considered as an immediate effective method for pain paroxysm of TGN.

AB - Background: Trigeminal neuralgia (TGN) is a challenging pain syndrome. Aim: To test the effectiveness of local instillation of ophthalmic solution of amethocaine in relieving the pain of TGN. Methods: We performed an open-label prospective study in 40 consecutive currently treated patients suffering from TGN with a reported visual analog scale (VAS).8 (severe pain). The patients received two drops of amethocaine 1% instilled on the cornea ipsilateral to the painful side. Pain score assessment using VAS was recorded pre- and post-treatment. Results: A total of 32 (80%) patients reported a significant reduction in pain 10 minutes after drops instillation as compared with pre-treatment pain score. Pre-treatment VAS score was 8.53 ± 0.6 as compared with 4.78 ± 1.83 post-amethocaine treatments (P, 0.00001). Conclusion: Topical ophthalmic instillation of amethocaine 1% can be considered as an immediate effective method for pain paroxysm of TGN.

KW - Amethocaine

KW - Ophthalmic

KW - Pain

KW - Trigeminal neuralgia

UR - http://www.scopus.com/inward/record.url?scp=78650727123&partnerID=8YFLogxK

U2 - 10.2147/LRA.S14281

DO - 10.2147/LRA.S14281

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:78650727123

SN - 1178-7112

VL - 3

SP - 155

EP - 157

JO - Local and Regional Anesthesia

JF - Local and Regional Anesthesia

IS - 1

ER -

Topical ophthalmic amethocaine alleviates trigeminal neuralgia pain

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this