Tongue Lumps and Bumps: Histopathological Dilemmas and Clues for Diagnosis

Irit Allon*, Marilena Vered, Ilana Kaplan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Exophytic lesions of the tongue encompass a diverse spectrum of entities. These are most commonly reactive, arising in response to local trauma but can also be neoplastic of epithelial, mesenchymal or miscellaneous origin. In most cases, the microscopic examination is likely to provide a straightforward diagnosis. However, some cases can still raise microscopic diagnostic dilemmas, such as conditions that mimic malignancies, benign tumors with overlapping features and anecdotal lesions. A series of “lumps and bumps” of the tongue are presented together with suggested clues that can assist in reaching a correct diagnosis, emphasizing the importance of the clinico-pathological correlations.

Original languageEnglish
Pages (from-to)114-124
Number of pages11
JournalHead and Neck Pathology
Issue number1
StatePublished - 15 Mar 2019


  • Adipocytic tumors
  • Lumps and bumps
  • Lymphoid-rich lesions
  • Neural lesion
  • Pseudoepitheliomatous hyperplasia
  • Spindle cell tumors
  • Tongue
  • Verrucous lesions


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