Timing of testicular sperm retrieval procedures and in vitro fertilization-intracytoplasmic sperm injection outcome

David Levran, Shimon Ginath, Jacob Farhi, Hana Nahum, Marek Glezerman, Ariel Weissman

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To compare the outcome of IVF-intracytoplasmic sperm injection (ICSI) using testicular spermatozoa obtained on the day of ovum pick-up (OPU) or on the day before OPU. Design: Retrospective study. Setting: An IVF clinic in a university hospital. Patient(s): Forty-seven IVF-ICSI cycles using testicular spermatozoa in 28 couples with the male partner suffering from nonobstructive azoospermia. Intervention(s): Sperm retrieval was performed either on the OPU day (23 cycles in 19 patients; group A) or on the day before OPU (24 cycles in 15 patients; group B). Testicular sperm aspiration (TESA) was performed and followed by testicular sperm extraction (TESE) if no spermatozoa could be found. Main Outcome Measure(s): The presence of motile spermatozoa at the time of ICSI and fertilization and clinical pregnancy rates. Result(s): A similar proportion of motile spermatozoa (60.9% vs. 62.5%), fertilization rate (61.7% vs. 58.9%), and clinical pregnancy rate per transfer (34.8% and 29.2%) were obtained for groups A and B, respectively. Conclusion(s): Testicular sperm retrieval can be performed on the day before OPU without compromising success. Considerable medical and practical advantages may be offered by further advancement of testicular sperm retrieval procedures to 48 hours before OPU. This approach should thus be further evaluated.

Original languageEnglish
Pages (from-to)380-383
Number of pages4
JournalFertility and Sterility
Volume76
Issue number2
DOIs
StatePublished - 2001

Keywords

  • Azoospermia
  • ICSI
  • IVF
  • Male infertility
  • Testicular sperm aspiration
  • Testicular sperm extraction

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