Time lapse microscopy is useful for elective single-embryo transfer

Einat Haikin Herzberger; Yehudith Ghetler; Rina Tamir Yaniv; Arie Berkovitz; Ofer Gonen; Ilan Cohen; Adrian Shulman; Amir Wiser

doi:10.1080/09513590.2016.1188375

Time lapse microscopy is useful for elective single-embryo transfer

Einat Haikin Herzberger^*, Yehudith Ghetler, Rina Tamir Yaniv, Arie Berkovitz, Ofer Gonen, Ilan Cohen, Adrian Shulman, Amir Wiser

^*Corresponding author for this work

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The aim of our study was to evaluate time lapse microscopy (TLM) as a selection tool for single-embryo transfer (SET) on day 5, blastocyst stage. An observational cohort study was conducted. Patients who had SET were compared to patients who had double embryo transfer (DET). A total of 108 patients were included in analysis, 83 had SET, and 25 underwent DET. Embryos were incubated and evaluated using TLM. The pregnancy rates were similar between the groups (42.2% in SET and 48.0% in DET). However, the multiple pregnancy rate was significantly higher in the DET group compared to the SET group (41.7% versus 2.9%, respectively; p < 0.001). This study concludes that SET with TLM do not decrease pregnancy rates compared to DET. However, transfers of two embryos increase the rate of multiple pregnancies.

Original language	English
Pages (from-to)	816-818
Number of pages	3
Journal	Gynecological Endocrinology
Volume	32
Issue number	10
DOIs	https://doi.org/10.1080/09513590.2016.1188375
State	Published - 2 Oct 2016

Keywords

Embryo selection
multiple pregnancies
single-embryo transfer
time lapse imaging

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10.1080/09513590.2016.1188375

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title = "Time lapse microscopy is useful for elective single-embryo transfer",

abstract = "The aim of our study was to evaluate time lapse microscopy (TLM) as a selection tool for single-embryo transfer (SET) on day 5, blastocyst stage. An observational cohort study was conducted. Patients who had SET were compared to patients who had double embryo transfer (DET). A total of 108 patients were included in analysis, 83 had SET, and 25 underwent DET. Embryos were incubated and evaluated using TLM. The pregnancy rates were similar between the groups (42.2% in SET and 48.0% in DET). However, the multiple pregnancy rate was significantly higher in the DET group compared to the SET group (41.7% versus 2.9%, respectively; p < 0.001). This study concludes that SET with TLM do not decrease pregnancy rates compared to DET. However, transfers of two embryos increase the rate of multiple pregnancies.",

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AU - Ghetler, Yehudith

AU - Tamir Yaniv, Rina

AU - Berkovitz, Arie

AU - Gonen, Ofer

AU - Cohen, Ilan

AU - Shulman, Adrian

AU - Wiser, Amir

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Time lapse microscopy is useful for elective single-embryo transfer

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Keywords

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