Time-dependent gene expression analysis of the developing superior olivary complex

Heike Ehmann, Heiner Hartwich, Christian Salzig, Nadja Hartmann, Mathieu Clement-Ziza, Kathy Ushakov, Karen B. Avraham, Olaf R.P. Bininda-Emonds, Alexander K. Hartmann, Patrick Lang, Eckhard Friauf, Hans Gerd Nothwang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background: The superior olivary complex (SOC) is an essential center for spatial hearing. Results: Generation of a comprehensive qualitative and quantitative catalogue of the developmental changes in the SOC-related gene repertoire. Conclusion: Postnatal maturation of the SOC is shaped by extensive molecular changes. Significance: This work identifies strong candidate genes for normal and impaired hearing and genetic evidence for retrocochlear functions of deafness genes.

Original languageEnglish
Pages (from-to)25865-25879
Number of pages15
JournalJournal of Biological Chemistry
Issue number36
StatePublished - 6 Sep 2013


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