Tiapride as treatment for certain patients with idiopathic torsion dystonia

A. Arlazoroff*, Colin Klein, Zeev Meiner, Ron Milo, Jacques Theitler, Clive L. Carpel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Five female patients with idiopathic torsion dystonia (ITD) responded to treatment with tiapride, a selective D-2 dopamine antagonist. Previous treatments with various drugs, including anticholinergics, were ineffective. It is suggested that the previously reported genetic subgroups of ITD respond to different drug regimens. The autosomal dominant group responded to anticholinergics, while the autosomal recessive group responded best to a selective D-2 dopamine antagonist.

Original languageEnglish
Pages (from-to)356-359
Number of pages4
JournalEuropean Neurology
Volume31
Issue number6
DOIs
StatePublished - 1991

Keywords

  • Idiopathic torsion dystonia
  • Involuntary movements
  • Tiapride

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