In order to investigate whether the thyroid gland, an organ of endodermal origin, is affected in cystic fibrosis (CF), thyroid metabolism was investigated in CF patients ranging in age from 1 to 20 yr. There is no gross disturbance of peripheral concentrations of T4 or T3, nor of the thyroid binding in the serum of CF patients. The peripheral conversion of T4 to T3 is normal. The increase in rT3 concentrations in CF patients suggests a preferential production of this hormone. It seems that this is not due to malnutrition alone and might be due to chronic hypoxia.
|Number of pages||3|
|Journal||Israel Journal of Medical Sciences|
|State||Published - 1983|