TY - JOUR
T1 - Thyroid disorders during pregnancy
AU - Parkes, Ilana L.
AU - Schenker, Joseph G.
AU - Shufaro, Yoel
PY - 2012/12
Y1 - 2012/12
N2 - Thyroid physiology is altered during pregnancy as a result of an increase in thyroid-binding globulin, the stimulatory effect of hCG on TSH receptors, and increased peripheral thyroid hormone requirements. In addition, hyper and hypothyroid disorders are prevalent among women of reproductive age, and most of them have a significant impact on the gravida, fetus and neonate. Aberrant thyroid function can be readily recognized and treated during pregnancy, avoiding such complications. Here, we will review the thyroid function changes occurring during pregnancy, the different disorders, their maternal and fetal implications, and the ways to screen, prevent and treat these conditions.
AB - Thyroid physiology is altered during pregnancy as a result of an increase in thyroid-binding globulin, the stimulatory effect of hCG on TSH receptors, and increased peripheral thyroid hormone requirements. In addition, hyper and hypothyroid disorders are prevalent among women of reproductive age, and most of them have a significant impact on the gravida, fetus and neonate. Aberrant thyroid function can be readily recognized and treated during pregnancy, avoiding such complications. Here, we will review the thyroid function changes occurring during pregnancy, the different disorders, their maternal and fetal implications, and the ways to screen, prevent and treat these conditions.
KW - Hyperthyroidism
KW - Hypothyroidism
KW - Pregnancy
UR - http://www.scopus.com/inward/record.url?scp=84870039803&partnerID=8YFLogxK
U2 - 10.3109/09513590.2012.692001
DO - 10.3109/09513590.2012.692001
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C2 - 22686167
AN - SCOPUS:84870039803
SN - 0951-3590
VL - 28
SP - 993
EP - 998
JO - Gynecological Endocrinology
JF - Gynecological Endocrinology
IS - 12
ER -