Thymidine incorporation into Pharbitis DNA: I. Adenosine effects on degradation by the thymidine phosphorylase system

Aviah Zilberstein*, Tova Arzee, J. Gressel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Much of the 3H-methyl thymidine supplied to Pharbitis is degraded by thymidine phosphorylase (E.C.2.4.2.4.) to thymine and by other enzymes to β-amino isobutyric acid and presumably further to CO2 + water. At a certain time, adenosine application partially prevents this degradation at the level of thymidine to thymine, and also thymine to β-amino isobutyric acid.

Original languageEnglish
Pages (from-to)205-211
Number of pages7
JournalCell Differentiation
Volume2
Issue number4
DOIs
StatePublished - Oct 1973

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