Thrombolytic therapy of a stenosed coronary vein bypass graft with continuous intragraft streptokinase drip

Morris Mosseri, Yonathan Hasin, Dan Admon, Mervyn S. Gotsman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A patient with newly onset angina due to recent thrombotic occlusion of a saphenous vein graft to the left anterior descending coronary artery is described. The patient was successfully treated by a direct intragraft infusion of streptokinase (STK) followed by a continuous intragraft infusion of an additional 1.5 million units of STK during the next 20 h through a regular diagnostic catheter. The patient was discharged on oral anticoagulant treatment with remarkable relief of the angina. Repeat angiography showed complete dissolution of the graft thrombus. This patient demonstrates that continuous infusion of STK into a saphenous vein graft is an effective treatment for recently formed thrombi.

Original languageEnglish
Pages (from-to)318-321
Number of pages4
JournalCardiology
Volume77
Issue number4
DOIs
StatePublished - 1990
Externally publishedYes

Keywords

  • Fibrinolysis
  • Graft occlusion
  • Saphenous vein

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