TY - JOUR
T1 - Thrombolysis in the eyes of the continuous wavelet transform
AU - Toledo, E.
AU - Gurevitz, O.
AU - Hod, H.
AU - Eldar, M.
AU - Akselrod, Solange
PY - 2002
Y1 - 2002
N2 - Acute myocardial infarction (MI) is known to elicit autonomic responses, depending on its location: inferior-wall MI (Inf-MI) promotes vagal activation, and anterior-wall MI (Ant-MI) promotes sympathetic activation. Reperfusion is thus expected to induce an opposite shift in autonomic balance. We studied the patterns of heart rate variability (HRV), which reflect the autonomic response to reperfusion by applying a continuous wavelet transform (CWT), ECG traces, 3 h long, were obtained from 9 Ant-MI and 8 Inf-MI patients during acute MI. Marked alterations in HRV occured in all reperfusion events. A shift in balance towards sympathetic predominance was found in all Inf-MI patients, and in 3 Ant-MI patients, while a shift towards vagal predominance was found in 6 Ant-MI patients (p<0.001). The CWT thus enables to study cardiac control during non-steady-state conditions, as exhibited during thrombolysis.
AB - Acute myocardial infarction (MI) is known to elicit autonomic responses, depending on its location: inferior-wall MI (Inf-MI) promotes vagal activation, and anterior-wall MI (Ant-MI) promotes sympathetic activation. Reperfusion is thus expected to induce an opposite shift in autonomic balance. We studied the patterns of heart rate variability (HRV), which reflect the autonomic response to reperfusion by applying a continuous wavelet transform (CWT), ECG traces, 3 h long, were obtained from 9 Ant-MI and 8 Inf-MI patients during acute MI. Marked alterations in HRV occured in all reperfusion events. A shift in balance towards sympathetic predominance was found in all Inf-MI patients, and in 3 Ant-MI patients, while a shift towards vagal predominance was found in 6 Ant-MI patients (p<0.001). The CWT thus enables to study cardiac control during non-steady-state conditions, as exhibited during thrombolysis.
UR - http://www.scopus.com/inward/record.url?scp=0036955669&partnerID=8YFLogxK
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AN - SCOPUS:0036955669
SN - 0276-6574
VL - 29
SP - 657
EP - 660
JO - Computers in Cardiology
JF - Computers in Cardiology
T2 - Computers in Cardiology 2002
Y2 - 22 September 2002 through 25 September 2002
ER -