Thrombolysis in the eyes of the continuous wavelet transform

E. Toledo, O. Gurevitz, H. Hod, M. Eldar, Solange Akselrod*

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review


Acute myocardial infarction (MI) is known to elicit autonomic responses, depending on its location: inferior-wall MI (Inf-MI) promotes vagal activation, and anterior-wall MI (Ant-MI) promotes sympathetic activation. Reperfusion is thus expected to induce an opposite shift in autonomic balance. We studied the patterns of heart rate variability (HRV), which reflect the autonomic response to reperfusion by applying a continuous wavelet transform (CWT), ECG traces, 3 h long, were obtained from 9 Ant-MI and 8 Inf-MI patients during acute MI. Marked alterations in HRV occured in all reperfusion events. A shift in balance towards sympathetic predominance was found in all Inf-MI patients, and in 3 Ant-MI patients, while a shift towards vagal predominance was found in 6 Ant-MI patients (p<0.001). The CWT thus enables to study cardiac control during non-steady-state conditions, as exhibited during thrombolysis.

Original languageEnglish
Pages (from-to)657-660
Number of pages4
JournalComputers in Cardiology
StatePublished - 2002
EventComputers in Cardiology 2002 - Memphis, TN, United States
Duration: 22 Sep 200225 Sep 2002


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