TY - JOUR
T1 - THROMBASTHENIA
T2 - A STUDY OF TWO SIBLINGS
AU - Zaizov, R.
AU - Cohen, I.
AU - Matoth, Y.
PY - 1968/11
Y1 - 1968/11
N2 - Clinical and laboratory observations on a brother and sister with congenital hemorrhagic disorder are presented. Both had prolonged bleeding time, poor clot retraction and failure of the platelets to aggregate and adhere to glass in the presence of ADP, absence of platelet extractable fibrinogen and impairment of platelet factor 3 availability. The abnormal platelet function, confirms the recent diagnostic criteria of thrombasthenia. Coagulation studies in the parents were normal. The hemostatic abnormality in thrombasthenia is discussed.
AB - Clinical and laboratory observations on a brother and sister with congenital hemorrhagic disorder are presented. Both had prolonged bleeding time, poor clot retraction and failure of the platelets to aggregate and adhere to glass in the presence of ADP, absence of platelet extractable fibrinogen and impairment of platelet factor 3 availability. The abnormal platelet function, confirms the recent diagnostic criteria of thrombasthenia. Coagulation studies in the parents were normal. The hemostatic abnormality in thrombasthenia is discussed.
KW - Thrombasthenia
KW - abnormal platelet function
UR - http://www.scopus.com/inward/record.url?scp=0014351404&partnerID=8YFLogxK
U2 - 10.1111/j.1651-2227.1968.tb06973.x
DO - 10.1111/j.1651-2227.1968.tb06973.x
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C2 - 5706368
AN - SCOPUS:0014351404
SN - 0803-5253
VL - 57
SP - 522
EP - 526
JO - Acta Paediatrica, International Journal of Paediatrics
JF - Acta Paediatrica, International Journal of Paediatrics
IS - 6
ER -