Three sibs with microcephaly, clubfeet and agenesis of corpus callosum: A new genetic syndrome?

Vered Shkalim*, Liat Ben-Sira, Dov Inbar, Walid Kaadan, Lina Basel-Vanagaite, Rachel Straussberg

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Clubfoot is a common birth deformity, and agenesis of the corpus callosum is one of the most prevalent brain malformations. We describe three sibs of Arab origin, who were born with clubfeet, agenesis of corpus callosum, and minor anomalies. Two of them were born with microcephaly. This phenotype may represent a novel autosomal recessive genetic condition.

Original languageEnglish
Pages (from-to)1060-1065
Number of pages6
JournalAmerican Journal of Medical Genetics, Part A
Volume155
Issue number5
DOIs
StatePublished - May 2011

Keywords

  • Agenesis of corpus callosum
  • Clubfoot
  • Microcephaly
  • Minor anomalies

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