Three novel metabolites from a bloom of the cyanobacterium Microcystis sp.

Shiri Gesner-Apter, Shmuel Carmeli

Research output: Contribution to journalArticlepeer-review

Abstract

Three new metabolites, microphycin AL828, microguanidine AL772, and microginin AL584 and three known metabolites, anabaenopeptin F, oscillamide Y, and microcin SF608 were isolated from the extracts of a Microcystis sp. bloom collected in Alonim reservoir, Valley of Armagedon, Israel. The planar structure of the compounds was determined by homonuclear and inverse-heteronuclear 2D-NMR techniques as well as high-resolution mass spectrometry. The absolute configuration of the asymmetric centers of the amino acids was studied using Marfey's method for HPLC.

Original languageEnglish
Pages (from-to)6628-6634
Number of pages7
JournalTetrahedron
Volume64
Issue number28
DOIs
StatePublished - 7 Jul 2008

Keywords

  • Cyanobacteria
  • Microcystis
  • Natural products

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