Three new cytotoxic metabolites from the marine sponge Plakortis halichondrioides

Amira Rudi, Yoel Kashman

Research output: Contribution to journalArticlepeer-review

Abstract

Three new cytotoxic compounds, one a cyclic-peroxide-containing acid (5) and the two others alkylated dihydroxy α,β-unsaturated C22 and C21 acids (6 and 7), were isolated from the marine sponge Plakortis halichondrioides, which was collected off the coast of Jamaica. The structures were elucidated through mass and mainly 1D and 2D nmr spectral analysis. All three acids are cytotoxic against P-388 murine leukemia.

Original languageEnglish
Pages (from-to)1827-1830
Number of pages4
JournalJournal of Natural Products
Volume56
Issue number10
DOIs
StatePublished - Oct 1993

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