Three new cytotoxic metabolites from the marine sponge Plakortis halichondrioides

Amira Rudi; Yoel Kashman

doi:10.1021/np50100a027

Three new cytotoxic metabolites from the marine sponge Plakortis halichondrioides

Amira Rudi, Yoel Kashman

School of Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Three new cytotoxic compounds, one a cyclic-peroxide-containing acid (5) and the two others alkylated dihydroxy α,β-unsaturated C₂₂ and C₂₁ acids (6 and 7), were isolated from the marine sponge Plakortis halichondrioides, which was collected off the coast of Jamaica. The structures were elucidated through mass and mainly 1D and 2D nmr spectral analysis. All three acids are cytotoxic against P-388 murine leukemia.

Original language	English
Pages (from-to)	1827-1830
Number of pages	4
Journal	Journal of Natural Products
Volume	56
Issue number	10
DOIs	https://doi.org/10.1021/np50100a027
State	Published - Oct 1993

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1021/np50100a027

Cite this

@article{4ad62386f71c453fb2a77c7824cd6866,

title = "Three new cytotoxic metabolites from the marine sponge Plakortis halichondrioides",

abstract = "Three new cytotoxic compounds, one a cyclic-peroxide-containing acid (5) and the two others alkylated dihydroxy α,β-unsaturated C22 and C21 acids (6 and 7), were isolated from the marine sponge Plakortis halichondrioides, which was collected off the coast of Jamaica. The structures were elucidated through mass and mainly 1D and 2D nmr spectral analysis. All three acids are cytotoxic against P-388 murine leukemia.",

author = "Amira Rudi and Yoel Kashman",

year = "1993",

month = oct,

doi = "10.1021/np50100a027",

language = "אנגלית",

volume = "56",

pages = "1827--1830",

journal = "Journal of Natural Products",

issn = "0163-3864",

publisher = "American Chemical Society",

number = "10",

}

TY - JOUR

T1 - Three new cytotoxic metabolites from the marine sponge Plakortis halichondrioides

AU - Rudi, Amira

AU - Kashman, Yoel

PY - 1993/10

Y1 - 1993/10

N2 - Three new cytotoxic compounds, one a cyclic-peroxide-containing acid (5) and the two others alkylated dihydroxy α,β-unsaturated C22 and C21 acids (6 and 7), were isolated from the marine sponge Plakortis halichondrioides, which was collected off the coast of Jamaica. The structures were elucidated through mass and mainly 1D and 2D nmr spectral analysis. All three acids are cytotoxic against P-388 murine leukemia.

AB - Three new cytotoxic compounds, one a cyclic-peroxide-containing acid (5) and the two others alkylated dihydroxy α,β-unsaturated C22 and C21 acids (6 and 7), were isolated from the marine sponge Plakortis halichondrioides, which was collected off the coast of Jamaica. The structures were elucidated through mass and mainly 1D and 2D nmr spectral analysis. All three acids are cytotoxic against P-388 murine leukemia.

UR - http://www.scopus.com/inward/record.url?scp=0027489190&partnerID=8YFLogxK

U2 - 10.1021/np50100a027

DO - 10.1021/np50100a027

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:0027489190

VL - 56

SP - 1827

EP - 1830

JO - Journal of Natural Products

JF - Journal of Natural Products

SN - 0163-3864

IS - 10

ER -

Three new cytotoxic metabolites from the marine sponge Plakortis halichondrioides

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this