Three conservative approaches to treatment of interstitial pregnancy

Ron Sagiv, Abraham Golan, Sagit Arbel-Alon, Marek Glezerman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


Interstitial pregnancy is among the most dangerous types of ectopic pregnancy. Four such pregnancies in three women were treated by three conservative modalities with favorable results. A 10-week interstitial pregnancy was successfully treated by laparoscopic-guided local methotrexate (MTX) injection into the gestational sac. Six years later the same woman had a repeat unruptured interstitial pregnancy at 9 weeks' gestation, with the gestational sac located in the same location as the previous one. Laparoscopic cornuostomy was performed. An asymptomatic woman in the eighth week of an interstitial pregnancy was treated with systemic MTX, but despite decreasing β-human chorionic gonadotropin levels, cornual rupture occurred. The patient was successfully treated by laparoscopic cornuostomy. The final patient was admitted in hypovolemic shock and hemoperitoneum and was treated successfully for ruptured 8-week interstitial pregnancy by laparoscopic cornuostomy.

Original languageEnglish
Pages (from-to)154-158
Number of pages5
JournalJournal of the American Association of Gynecologic Laparoscopists
Issue number1
StatePublished - 2001


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