Thin unresponsive endometrium - A possible complication of surgical curettage compromising ART outcome

Yoel Shufaro, Alex Simon, Neri Laufer, Muhammad Fatum

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: Endometrial thickness is important for implantation. Little data addresses the etiology of persistently thin endometrium. We present a patient cohort in order to define common features and draw conclusions. Methods: Thirteen out of 1,405 IVF patients repeatedly had thin unresponsive endometrium (<7 mm). Age, history, uterine cavity status, treatment type and outcome were examined. Results: Patient age was 35.9±5.7 years. Ten patients had a curettage performed previously. Nine patients had normal cavity and endometrium, and in four adhesions were diagnosed and removed. Out of 99 cycles performed afterwards, endometrial thickness increased in 22. ETs were performed in 49 cycles resulting in 11 pregnancies. Their outcome was eight miscarriages, two terminations due to malformations, and one live birth. Conclusions: Thin unresponsive endometrium was associated with curettage, not necessarily with intrauterine adhesions. Even if adequate thickening eventually occurred, the reproductive outcome was still very poor. Therefore other alternatives should be sought for these patients.

Original languageEnglish
Pages (from-to)421-425
Number of pages5
JournalJournal of Assisted Reproduction and Genetics
Volume25
Issue number8
DOIs
StatePublished - Aug 2008
Externally publishedYes

Keywords

  • ART
  • Curettage
  • Thin and unresponsive endometrium

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