Thin endometrium in donor oocyte recipients: Enigma or obstacle for implantation?

Lena Dain, David Bider, Jacob Levron, Viktor Zinchenko, Sharon Westler, Martha Dirnfeld*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

55 Scopus citations

Abstract

Objective To evaluate the combined effect of endometrial thickness and anatomic uterine factors on clinical outcome in oocyte donation recipients. Design Retrospective analysis of oocyte donation cycles conducted between 2005 and 2010. Setting Two private IVF centers. Patient(s) A total of 737 donor oocyte cycles. Intervention(s) None. Main Outcome Measure(s) Clinical pregnancy and live birth rates. Result(s) No statistically significant difference was found in clinical pregnancy rates and live birth rates in cycles with endometrial thickness <6 mm compared with those with endometrial thickness >10 mm. However, a relatively high rate of live births was found within a medium range of endometrial thickness (8.2-10 mm). All intrauterine adhesion cases occurred in cycles with thinner endometrium. Conclusion(s) No statistically significant difference was found in clinical pregnancy rates and live birth rates in cycles with endometrial thickness <6 mm compared with those with thickness >6 mm. A relatively high rate of live births was found within a medium range of endometrial thickness (9.1-10 mm).

Original languageEnglish
Pages (from-to)1289-1295.e2
JournalFertility and Sterility
Volume100
Issue number5
DOIs
StatePublished - Nov 2013
Externally publishedYes

Keywords

  • Endometrial thickness
  • estrogen replacement therapy
  • oocyte donation
  • uterine factors

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