Purpose; Amhocynosides in a multiple oral dose reportedly improve night vision tests in normal individuals. We evaluated in this study the effect of multiple oral anlhocyanosidcs administration on 1 night vision tests, wholefield scolopic retinal threshold (SRT), mesopic contrast sensitivity (MCS) and dark adaptation rate (DAR) These 3 night vision tests have a significant predicthc value of the ability to detect real targets at night. Materials and Methods: In this double blin1, placebo controlled. cross-over study 18 young volunteers were randomh assignee to a multiple oral administration of anthocyanosides or placebo Amhocyanosides (bluebcrn extract tablets iStnxi which contain 12mg anthocyanoside per labiet) and placebo (ground food starch) were given as a gift (CTS. Israel) Anthocyanosides were given in doses of 12mg or 24mg twice daiK for 4 days DAR, SRT and MCS were studied immediately before and ai day 1, 2, 3 and 4 during the treatment period. Results: No significant effect was found on my of the above mentioned night vision tests during 4 days oral administration of 12mg or 24mg anthoaanosidcs twice daily. Conclusion: Multiple oral anthocvanosides .idmmistiation of 12mg and 24mg twice a day appears to lack significant effect on night vision tests.
|Journal||Investigative Ophthalmology and Visual Science|
|State||Published - 1997|