Thermotropic properties of calf-brain lipids interacting with drugs-II

D. Bach*, B. Sela

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The influence of different drugs on the thermotropic properties of calf-brain lipids was investigated. Tetracaine, ethanol and ketamine caused a downward shift in the temperature of the maximum in the heat flow, with almost no change in the enthalpy of melting of the lipids. However, cannabinoids caused a decrease in the enthalpy of melting, accompanied by a minor shift in the melting temperature. The effect of cholesterol on drug interactions was also investigated.

Original languageEnglish
Pages (from-to)1777-1780
Number of pages4
JournalBiochemical Pharmacology
Volume30
Issue number13
DOIs
StatePublished - 1 Jul 1981
Externally publishedYes

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