TY - GEN
T1 - Theoretical analysis of coronary flow regulation
AU - Barnea, O.
PY - 1992
Y1 - 1992
N2 - The purpose is to present a parameter which is related to cardiac oxygen reserve and demonstrate its usefulness in studying coronary autoregulation. In proposing this parameter, it is assumed that myocardial oxygen supply and consumption are equal under steady state condition. This assumption allows the use of the value of oxygen consumption as an estimate of oxygen supply. Coronary resistance to oxygen flow is defined and used to study the response of coronary autoregulation to changes in cardiac contractility and preload. Using this parameter, which indicates coronary reserve, the author was able to demonstrate an optimal contractility level for which coronary resistance to oxygen flow is maximal.
AB - The purpose is to present a parameter which is related to cardiac oxygen reserve and demonstrate its usefulness in studying coronary autoregulation. In proposing this parameter, it is assumed that myocardial oxygen supply and consumption are equal under steady state condition. This assumption allows the use of the value of oxygen consumption as an estimate of oxygen supply. Coronary resistance to oxygen flow is defined and used to study the response of coronary autoregulation to changes in cardiac contractility and preload. Using this parameter, which indicates coronary reserve, the author was able to demonstrate an optimal contractility level for which coronary resistance to oxygen flow is maximal.
UR - http://www.scopus.com/inward/record.url?scp=0026711719&partnerID=8YFLogxK
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AN - SCOPUS:0026711719
SN - 081862485X
T3 - Computers in Cardiology
SP - 657
EP - 659
BT - Computers in Cardiology
PB - Publ by IEEE
T2 - Proceedings of the 18th Annual Conference on Computers in Cardiology
Y2 - 23 September 1991 through 26 September 1991
ER -