The value of stress thallium-201 single photon emission CT imaging as a predictor of outcome and long-term prognosis after CABG

Itzhak Shapira, Israel Heller, Yulia Kornizky, Marcel Topilsky, Aharon Isakov

Research output: Contribution to journalArticlepeer-review

Abstract

This study examined the capability of rest-redistribution 201Tl single photon emission CT imaging (TSPECT) done shortly after coronary artery bypass grafting (CABG) to predict outcome and long term prognosis. Results of TSPECT at 5.5 ± 0.7 (range 4 - 8) months postoperatively were correlated during a 4-year follow-up period with mortality, major surgical and nonsurgical cardiac events and cardiac event-free survival in 170 patients who underwent CABG. Ten (5.8%) patients died during follow-up: 4 had a documented cardiac death (all of them with large or moderate reversible filling defects). In the survivors, there were 10 nonfatal myocardial infarctions and 11 revascularization interventions. Patients who eventually required and underwent revascularization procedures demonstrated large or moderate reversible filing defects, in contrast with those who had no need for an additional procedure (15.7% versus 2.5%, p < 0.001). Postoperative TSPECT carried out soon after CABG had definite prognostic value and should be performed routinely to help decide treatment protocol.

Original languageEnglish
Pages (from-to)271-282
Number of pages12
JournalJournal of Medicine
Volume32
Issue number5-6
StatePublished - 2001
Externally publishedYes

Keywords

  • Cardiac events
  • Cineangiography
  • Coronary artery bypass grafting
  • Prognosis
  • Rest-redistribution Tl single photon emission CT imaging
  • Revascularization interventions
  • Stress thallium scan
  • Thallium-201

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