@article{d84668048321467d8cf2f4f8d6173c91,
title = "The use of xenopus oocytes for the study of ion channel",
author = "Nathan Dascal",
note = "Funding Information: It is not clear what the functional role of muscarinic receptors is in the oocytes. A hint may come from the fact that muscarinic agonists promote progesterone-induced maturation.{\textquoteright}% The oocytes are extremely sensitive to ACh in this respect; doses as low as 1 nM (a level that may be found in blood) are already able to facilitate the maturation process.273 Endogenous ACh is found in oocytes in about the same concentrations as found in muscle.274 The source of this endogenous ACh is not clear, and any variations of its level have not been reported; one cannot disregard the possibility that this endogenous ACh may provide a means of fine regulation of the rate of maturation. This guess is supported by the fact that atropine slows the rate of progesterone-induced mat~ration.~H{\textquoteright}{\~o}w ever, this hypothesis lacks additional support, e.g., an indication of changes of ACh blood levels under different conditions, etc. Moreover, adenosine365a nd i n s ~ l i na~ls{\~o} p~ro.m{\~o} te, {\~o} r even initiate, maturation.",
year = "1987",
doi = "10.3109/10409238709086960",
language = "אנגלית",
volume = "22",
pages = "317--387",
journal = "Critical Reviews in Biochemistry and Molecular Biology",
issn = "1040-9238",
publisher = "Informa Healthcare",
number = "4",
}