TY - JOUR
T1 - The use of spectral-domain optical coherence tomography for differentiating long-standing central retinal artery occlusion and nonarteritic anterior ischemic optic neuropathy
AU - Dotan, Gad
AU - Goldenberg, Dafna
AU - Kesler, Anat
AU - Naftaliev, Elvira
AU - Loewenstein, Anat
AU - Goldstein, Michaella
PY - 2014/1
Y1 - 2014/1
N2 - BACKGROUND AND OBJECTIVE: To report on the efficacy of macular and optic nerve spectral-domain optical coherence tomography (SD-OCT) in differentiating between long-standing central retinal artery occlusion (CRAO) and nonarteritic anterior ischemic optic neuropathy (NAION). PATIENTS AND METHODS: SD-OCT scans of the macula and optic nerve in 24 patients with unilateral optic atrophy secondary to CRAO (12 patients) and NAION (12 patients) were compared both qualitatively and quantitatively for differentiating features. RESULTS: In patients with long-standing CRAO, there was a significantly greater (P < .001) thinning of the macula relative to the fellow uninvolved eye (-59.7 ± 31.8 μm) compared to patients with longstanding NAION (-19.9 ± 8.4 μm) even though both conditions caused a similar (P = .726) degree of peripapillary retinal nerve fiber layer loss (-42.4 ± 18.5 μm and -44.1 ± 12.4 μm, respectively). CONCLUSION: SD-OCT macular scans can be used as an adjunctive tool for differentiating between long-standing CRAO and NAION.
AB - BACKGROUND AND OBJECTIVE: To report on the efficacy of macular and optic nerve spectral-domain optical coherence tomography (SD-OCT) in differentiating between long-standing central retinal artery occlusion (CRAO) and nonarteritic anterior ischemic optic neuropathy (NAION). PATIENTS AND METHODS: SD-OCT scans of the macula and optic nerve in 24 patients with unilateral optic atrophy secondary to CRAO (12 patients) and NAION (12 patients) were compared both qualitatively and quantitatively for differentiating features. RESULTS: In patients with long-standing CRAO, there was a significantly greater (P < .001) thinning of the macula relative to the fellow uninvolved eye (-59.7 ± 31.8 μm) compared to patients with longstanding NAION (-19.9 ± 8.4 μm) even though both conditions caused a similar (P = .726) degree of peripapillary retinal nerve fiber layer loss (-42.4 ± 18.5 μm and -44.1 ± 12.4 μm, respectively). CONCLUSION: SD-OCT macular scans can be used as an adjunctive tool for differentiating between long-standing CRAO and NAION.
UR - http://www.scopus.com/inward/record.url?scp=84892572091&partnerID=8YFLogxK
U2 - 10.3928/23258160-20131220-05
DO - 10.3928/23258160-20131220-05
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C2 - 24392910
AN - SCOPUS:84892572091
SN - 2325-8160
VL - 45
SP - 38
EP - 44
JO - Ophthalmic Surgery Lasers and Imaging Retina
JF - Ophthalmic Surgery Lasers and Imaging Retina
IS - 1
ER -