The use of naproxen in the treatment of children with rheumatic fever

Yosef Uziel, Philip J. Hashkes, Eias Kassem, Shai Padeh, Ran Goldman, Baruch Vollach

Research output: Contribution to journalArticlepeer-review

Abstract

We evaluated the efficacy and safety of naproxen (10-20 mg/kg/d) for the treatment of arthritis and fever related to rheumatic fever in 19 children. Fever and arthritis resolved within a median of 1 day of beginning treatment (range, 1-2 and 1-30 days, respectively). The sole patient with prolonged arthritis had small joint involvement. No gastrointestinal, dermatologic, liver, or renal side effects were observed. None of the patients developed carditis over the following 6 months. Naproxen appears to be effective for the treatment of arthritis and fever related to rheumatic fever and is well tolerated.

Original languageEnglish
Pages (from-to)269-271
Number of pages3
JournalJournal of Pediatrics
Volume137
Issue number2
DOIs
StatePublished - 2000
Externally publishedYes

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